C. What are the symptoms of high transaminase Valley?
As the entire content of the liver transaminase levels in blood is about 100 times, if the release of the enzyme all remain active as long as 1% of liver cell necrosis, is enough to make the serum enzyme activity doubled. Also, because the liver cells in serum aminotransferase concentrations higher than 1000 ~ 5000-fold transaminase liver cells can also be a result of this concentration difference and leak into the blood. elevated alanine aminotransferase
reasons, there are many factors, such as: acute hepatitis, drugs (especially drugs on the liver damage), a long-term drinking or drinking large doses, and some biliary disease , when the heart failure, fever, and so the disease, can cause elevated alanine aminotransferase.
simple high transaminase (liver dysfunction) can not be identified as hepatitis, to determine the risk of hepatitis must meet the following three points was set up. That have hepatitis symptoms, signs (such as low-grade fever, tired of the oil, nausea, vomiting, fatigue, poor appetite, liver swelling, etc.) and clinical diagnosis (such as acute jaundice, chronic persistent type, etc.); increased serum transaminase; etiological diagnosis (with anti-hepatitis A antibodies are influenza, hepatitis B virus surface antigen, e antigen and hepatitis B core antibody-positive is). Some people simply transaminase high, do not rule out the detection of excessive drinking antecedents, strenuous exercise, night, cold or other factors interfere with certain medications orally.
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alanine aminotransferase of normal for 0-40u/L.
alanine aminotransferase mainly in the liver, heart and skeletal muscle. Liver cells or some tissue injury or necrosis, will cause the blood alanine aminotransferase increased, there are many clinical disease can cause abnormal aminotransferase, must be identified -
1, viral hepatitis is caused by the most elevated transaminase common diseases, various types of acute and chronic viral hepatitis can lead to transaminase elevation.
2, toxic hepatitis, a variety of drugs and chemicals can cause elevated transaminase, but after treatment, transaminases return to normal.
3, large or long-term drinkers will be elevated alanine aminotransferase.
4, cirrhosis and liver cirrhosis activities were higher than normal transaminase levels should be actively treated. 5, biliary tract disease, cholecystitis, cholelithiasis, acute attack, often fever, abdominal pain, nausea, vomiting, jaundice, blood bilirubin and transaminase elevation.
6, heart disease and acute myocardial infarction, myocarditis, heart failure, alanine aminotransferase and aspartate aminotransferase were increased, patients often have chest pain, palpitations, shortness of breath, swelling. There are positive signs, cardiac examination and ECG abnormalities.
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7, some other infectious diseases such as pneumonia, typhoid, tuberculosis, infectious mononucleosis psychosis have elevated transaminase phenomenon, but these diseases have typical clinical manifestations, and to experiment laboratory examination, diagnosis. In addition, acute soft tissue injury, strenuous exercise, pregnancy, also had transient transaminase elevation.
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